Alert:

Thank you for the continued interest in our product. Due to recent demand, availability may vary and certain inventory batches may sell out from time to time. We encourage customers to check the page below for the most current availability and shipping timelines.

Gavanci is offered with a 90-day money back guarantee so you can evaluate whether it fits your wellness routine with confidence.

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Ultimate Nano-Powered Esophageal & Stomach Support
Ultimate Nano-Powered Esophageal & Stomach Support
Ultimate Nano-Powered Esophageal & Stomach Support
Ultimate Nano-Powered Esophageal & Stomach Support
Ultimate Nano-Powered Esophageal & Stomach Support
Ultimate Nano-Powered Esophageal & Stomach Support
Ultimate Nano-Powered Esophageal & Stomach Support
Ultimate Nano-Powered Esophageal & Stomach Support

4.8/5 based on 10,000+ customers

Ultimate Nano-Powered Esophageal & Stomach Support

Top Rated Formula 2025

Awarded for excellence in digestive wellness innovation

Built to support esophageal tissue health and ease the daily impact of chronic reflux — the nighttime burning, the morning soreness, and the cough and mucus that antacids never fix. Refined through ongoing research and real-world feedback from 10,000+ customers.

A trusted choice for esophageal and digestive wellness support

Made with 11 carefully selected ingredients informed by scientific research

Formulated with nano technology
👀 Trending now! 24,000+ unit sold last month!

90-Day 100% Money Back Guarantee

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3rd Party Lab Tested
Title

Directions for Use:

Shake well. Pour 2 mL into a spoon and take twice daily before meals, or as directed by your healthcare practitioner. Alternatively, take 4 mL once at bedtime if discomfort worsens when lying down at night.

Ingredients

Carefully Designed for 
Digestive & Tissue Support

Overall gut and digestive wellness
 

Digestive comfort and occasional reflux-related discomfort

Soothing, coating comfort for the throat and esophagus

Antioxidant and immune-supportive activity
 

Try Gavanci™ Now

90-Day Money Back Guarantee

Top Rated Formula 2025

independent customer feedback

Unfiltered reviews from verified Gavanci buyers 

4.8/5 across 10,000+ orders

Julie Quinn.

Verified Buyer

my voice is finally coming back!!

1 day ago

honestly I was about to give up. for almost 3 years ive had this croaky throat and constant mucus, my voice was always rough and people at work kept asking if i was sick all the time. tried omeprazole then nexium then back to omeprazole again. nothing really fixed it, just covered it up for a few hours. saw an ad for gavanci and was skeptical cause ive tried so many things at this point. been taking it like 5 weeks and last weekend my husband actually said i sounded like myself again lol. not 100% yet but its a real difference. Will keep taking it and see how it goes!

Rachel Bennett

Verified Buyer

Worth trying if your stuck on PPIs

3 days ago

Was on prilosec for almost 10 years and when i tried coming off it the reflux came back twice as bad, doctor said its the rebound. found gavanci on facebook, price was better than esorepair so figured why not. 7 weeks in and had pizza last weekend without regretting it the next morning which is huge for me. only docking a star cause the bottle could last a bit longer

Daniel K.

Verified Buyer

I finally sleep thru the night, thanks!!

6 days ago

I started this maybe 6 weeks ago. The reason i bought it is cause the wedge pillow wasnt doing it anymore, neither was basically sleeping sitting up lol. I'd wake up coughing at 3am every single night with that burning going up into my throat. Took about 2 weeks before i noticed i was sleeping till 5, then eventually a full night. Not saying its a miracle but for the first time in probably 2 years i actually wanna go to bed. Still careful with what i eat at night but not as paranoid as i was...

Marcus Henderson

Verified Buyer

skeptical at first but the cough is gone

2 weeks ago

I had acid reflux for like 8 years, tried omeprazole and nexium and both stopped working after a while. ordered gavanci mostly cause of the 90 day guarantee, figured worst case id get my money back. took about 3-4 weeks but i havent reached for tums in over a month now which hasnt happened in years tbh

Comprehensive Upper Digestive Wellness Support

One serving provides targeted support for the upper digestive tract, helping maintain digestive comfort, soothe occasional throat irritation, and support healthy esophageal tissue as part of your daily wellness routine.

  • Tissue &

     Mucosal Support

  • Digestive 

    Soothing

  • Throat 

    Soothing

  • Healthy Inflammatory Balance Support

  • Mucosal 

    Barrier

  • Advanced Liquid Delivery System

Tissue & Mucosal Support

- ZINC-L-CARNOSINE • DGL • SLIPPERY ELM

Provides nutrients and botanical compounds that support healthy mucosal tissue, cellular integrity, and the natural maintenance of the upper digestive tract, including the throat and esophagus.

Digestive Soothing

- SODIUM ALGINATE • HYALURONIC ACID • CHONDROITIN

Helps support a soothing, coating effect and overall upper digestive comfort, while supporting the integrity of sensitive mucosal tissues in the throat and esophagus as part of normal digestive function.

Throat Soothing

- MARSHMALLOW ROOT • SLIPPERY ELM • ALOE VERA 

Features naturally soothing botanical ingredients traditionally used to help support throat comfort and upper digestive ease, with gentle mucilage compounds that help coat and support the natural lining of the upper digestive tract.

Healthy Inflammatory Balance Support

- VITAMIN D3 • QUERCETIN • ALOE VERA

Includes nutrients and botanical compounds that support a healthy inflammatory response and antioxidant activity, helping maintain overall upper digestive and mucosal wellness as part of normal physiological function.

Mucosal Barrier

- DGL LICORICE • HYALURONIC ACID 

•  L-GLUTAMINE

Supports the natural mucosal lining of the digestive tract, helping maintain its protective function and overall tissue health in the presence of everyday dietary and environmental irritants.

Advanced Liquid Delivery System

- ADVANCED NANO TECHNOLOGY

Designed as a liquid formula to help disperse ingredients evenly throughout the upper digestive tract during use, supporting convenient absorption and consistent ingredient distribution compared to traditional solid formats.

understanding upper
digestive comfort

The esophagus is routinely exposed to everyday dietary and lifestyle factors that can influence digestive comfort. Occasional irritation and discomfort may occur as part of normal digestive processes, especially after meals or when lying down.
 

Supporting the Esophageal Lining: The esophageal mucosa helps maintain a natural protective barrier and overall tissue integrity. Providing targeted nutritional and soothing support can help maintain the health of this lining and promote ongoing upper digestive wellness as part of a daily routine.

why ongoing esophageal wellness matters

Cellular Changes Over Time

The esophageal lining can be sensitive to ongoing dietary and digestive stressors. Supporting mucosal integrity helps maintain long-term upper digestive wellness.

Structural Changes & Sensitivity

Occasional irritation may affect swallowing comfort and normal digestive function. Supporting tissue health helps promote comfortable, consistent digestive wellness.

Chest & Upper Digestive Discomfort

Digestive discomfort can sometimes be felt in the chest area, especially after meals or during digestive stress. Supporting esophageal and digestive comfort helps promote a more balanced experience.

Respiratory & Throat Sensitivity

Occasional throat irritation or coughing may be associated with upper digestive discomfort. Supporting throat and upper digestive comfort contributes to overall wellness.

Sleep & Nighttime Comfort

Digestive discomfort may be more noticeable when lying down. Supporting nighttime digestive comfort can help promote restful sleep and daily well-being.

Oral & Dental Sensitivity

Upper digestive discomfort may occasionally extend to the throat or mouth. Maintaining digestive comfort supports overall oral and upper digestive wellness.

why nano technology changes everything

Standard esophageal supplements fail because their particles are too large to penetrate damaged tissue.

Gavanci uses nano technology to create particles Up to 1,000 times smaller than standard supplements. These ultra-fine nanoparticles encapsulate our supporting ingredients Marshmallow Root, DGL, Slippery Elm protecting them from stomach acid degradation while driving them directly into damaged esophageal cells.

The result? Up to 10x better absorption at the cellular level where true supporting occurs. That's why users feel soothing relief from their very first dose not weeks later.

the formulation

Precisely measured per serving and made with 11 carefully selected active ingredients designed to support esophageal and upper digestive wellness as part of a balanced daily routine.

Zinc-L-Carnosine 

75mg

A specialized mineral complex studied for its role in supporting mucosal tissue integrity and overall digestive lining health. Helps provide foundational nutritional support for normal cellular maintenance and upper digestive wellness.

DGL Extract (Deglycyrrhizinated Licorice) 90mg

Traditionally used botanical known for supporting digestive comfort and the natural protective lining of the upper digestive tract.

Slippery Elm Bark (Mucilage)

40mg

Rich in naturally occurring mucilage compounds that help provide gentle, soothing support for the throat and esophageal lining.

Aloe Vera (200:1 Extract) 

4.5mg solids (≈ 900mg fresh)

Concentrated botanical extract traditionally used to support digestive comfort and overall mucosal wellness.

Hyaluronic Acid 

22.5mg HA

A naturally occurring compound that supports tissue hydration and the integrity of mucosal surfaces throughout the upper digestive tract.

Marshmallow Root 10:1

22.5 mg (≈ 225 mg raw herb)

Contains soothing mucilage compounds traditionally used to support throat comfort and upper digestive ease.

Chondroitin Sulfate

90mg

A structural compound that supports the natural integrity and hydration of delicate mucosal tissues.

Sodium Alginate

11.25mg

A marine-derived compound commonly used in digestive wellness formulations to support upper digestive comfort and soothing support after meals.

L-Glutamine

45mg

An amino acid that supports the health and integrity of the digestive lining and overall gut barrier function.

Vitamin D3

50mcg

An essential nutrient that supports immune function and a healthy inflammatory response as part of overall digestive and mucosal wellness.

Quercetin 

22.5mg

A plant-derived antioxidant that helps support cellular health and a balanced inflammatory response within the digestive system.

Resources:

1. Wei J, Zhang J, Jiang Y, et al. Elevated Pro-inflammatory Cytokine Levels in Acute Reflux Esophagitis Are Reduced by 1,25-Dihydroxy Vitamin D₃. In Vivo. 2023;37(1):79-87. doi:10.21873/invivo.13056 — https://pubmed.ncbi.nlm.nih.gov/36593017/
 

2. Leiman DA, Riff BP, Morgan S, et al. Alginate Therapy Is Effective Treatment for GERD Symptoms: A Systematic Review and Meta-analysis. Dis Esophagus. 2017;30(5):1-9. doi:10.1093/dote/dow020 — https://pubmed.ncbi.nlm.nih.gov/28375448/
 

3. Hayashi K, Morita T, Itazawa T, et al. Polaprezinc Protects Against Radiation-Induced Esophagitis in Non-Small-Cell Lung-Cancer Patients Receiving Chemoradiotherapy. Int J Clin Oncol. 2016;21(4):670-676. PMID:27160234 — https://pubmed.ncbi.nlm.nih.gov/27160234/
 

4. Fink C, Schmidt M, Kraft K. Marshmallow Root Extract for the Treatment of Irritative Cough: Two Surveys on Users’ View on Effectiveness and Tolerability. Complement Med Res. 2018;25(5):299-305. doi:10.1159/000489560 — https://pubmed.ncbi.nlm.nih.gov/30064132/
 

5. dos Santos Rd, Viana ML, Generoso SV, et al. Glutamine supplementation decreases intestinal permeability and preserves gut mucosa integrity in an experimental mouse model. JPEN J Parenter Enteral Nutr. 2010;34(4):408-413. doi:10.1177/0148607110364181 — https://pubmed.ncbi.nlm.nih.gov/20631386/
 

6. Zhang W, Zhu B, Xu J, et al. Quercetin exerts anti-inflammatory effects via inhibiting TNF-α-induced MMP-9 expression in normal human gastric epithelial cells. World J Gastroenterol. 2022;28(11):1139-1155. doi:10.3748/wjg.v28.i11.1139 — https://www.wjgnet.com/1007-9327/full/v28/i11/1139.htm
 

7. Fink C, Schmidt M, Kraft K. Marshmallow root extract for the treatment of irritative cough: two surveys on users’ view on effectiveness and tolerability. Complement Med Res. 2018;25(5):299-305. doi:10.1159/000489560 — https://pubmed.ncbi.nlm.nih.gov/30064132/
 

8. Wei J, Zhang J, Jiang Y, et al. Elevated Pro-inflammatory Cytokine Levels in Acute Reflux Esophagitis Are Reduced by 1,25-Dihydroxy Vitamin D3. In Vivo. 2023;37(1):79-87. doi:10.21873/invivo.13056 https://pubmed.ncbi.nlm.nih.gov/36593017/
 

9. Lin P-H, Sermersheim M, Li H, et al. Zinc in Wound supporting Modulation. Nutrients. 2018;10(1):16. doi:10.3390/nu10010016 https://pubmed.ncbi.nlm.nih.gov/29295546/
 

10. Hayashi K, Morita T, Itazawa T, et al. Polaprezinc Protects Against Radiation-Induced Esophagitis in Non-Small-Cell Lung-Cancer Patients Receiving Chemoradiotherapy. Int J Clin Oncol. 2016;21:670-676. https://pubmed.ncbi.nlm.nih.gov/27160234/
 

11. Leiman DA, Riff BP, Morgan S, et al. Alginate Therapy Is Effective Treatment for GERD Symptoms: A Systematic Review and Meta-analysis. Dis Esophagus. 2017;30(5):1-9. doi:10.1093/dote/dow020 https://pubmed.ncbi.nlm.nih.gov/28375448/
 

12. Savarino V, Pace F, Scarpignato C; Esoxx Study Group. Mucosal Protection Plus Acid Suppression in Non-Erosive Reflux Disease: Efficacy of a Hyaluronic Acid–Chondroitin Sulfate Formulation. Aliment Pharmacol Ther. 2017;45:631-642. doi:10.1111/apt.13914
 

13. Fink C, Schmidt M, Kraft K. Marshmallow Root Extract for the Treatment of Irritative Cough: Two Surveys on Users’ View on Effectiveness and Tolerability. Complement Med Res. 2018;25(5):299-305. doi:10.1159/000489560 https://pubmed.ncbi.nlm.nih.gov/30064132/
 

14. Panahi Y, Khalili N, Hosseini S, et al. Efficacy and Safety of Aloe Vera Syrup for the Treatment of Gastro-Esophageal Reflux Disease: A Pilot Randomized Positive-Controlled Trial. J Tradit Chin Med. 2015;35(6):632-636. https://pubmed.ncbi.nlm.nih.gov/26880673/
 

15. Raj JP, Sivaperumal S, Peter AM, et al. GutGard in Managing Gastroesophageal Reflux-Related Symptoms: A Double-Blind Randomized Placebo-Controlled Trial. Complement Med Res. 2025;32(1):26-36. doi:10.1159/000543367
 

16. European Scientific Cooperative on Phytotherapy. Ulmus rubra (Slippery Elm) Bark—Monograph. ESCOP; 2019.
 

17. Abbasi F, Zamani F, Khalili H, et al. Oral Glutamine Supplementation and Intestinal Permeability: A Systematic Review and Meta-analysis. Amino Acids. 2024;56:60. doi:10.1007/s00726-024-03420-7
 

18. Zhang W, Zhu B, Xu J, et al. Quercetin Exerts Anti-Inflammatory Effects Via Inhibiting TNF-α-Induced MMP-9 Expression in Normal Human Gastric Epithelial Cells. World J Gastroenterol. 2022;28(11):1139-1155. doi:10.3748/wjg.v28.i11.1139 https://www.wjgnet.com/1007-9327/full/v28/i11/1139.htm
 

19. Tewari, A., Bapna, J. S., & Vohora, S. B. (1991). Clinical evaluation of deglycyrrhizinated liquorice in the management of [esophageal reflux].Indian Journal of Pharmacology.
 

20. Palmieri, B., Corbascio, D., & Merighi, A. (2013). Fixed combination of hyaluronic acid and chondroitin sulfate oral formulation in the treatment of gastroesophageal reflux: a randomized, double-blind, placebo-controlled clinical trial.European Review for Medical and Pharmacological Sciences, 17(24), 3272–3278.

what people ask us most

What is Gavanci™ and how does it work?

Gavanci is a liquid nano-delivery esophageal support supplement with 11 active ingredients. Unlike capsules or pills that rush straight to your stomach, Gavanci can be taken by the spoonful or mixed with water and sipped slowly, so the formula coats your entire esophageal tract on the way down. Our nano-delivery technology supports superior nutrient absorption, helping deliver soothing and protective ingredients directly to the tissue that needs it most.

What are the 11 active ingredients in it?

Gavanci contains Vitamin D3 (2,000 IU), Zinc (16.5 mg), Zinc-L-Carnosine / PepZin GI™ (75 mg), Sodium Alginate (30 mg), Hyaluronic Acid (100 mg), Chondroitin Sulfate (50 mg), Marshmallow Root Extract 10:1 (200 mg), Aloe Vera Inner-Leaf Gel 200:1 (10 mg), Deglycyrrhizinated Licorice / DGL (150 mg), Slippery Elm Bark Mucilage (200 mg), L-Glutamine (250 mg), and Quercetin (125 mg). Every ingredient is dosed to match levels used in published scientific research.

What does the product taste like?

It has a mild, slightly herbal taste that most customers find neutral to pleasant. It is unflavored and designed to be taken straight by the spoonful or mixed with ½ cup of water. Many customers describe it as easy to take daily. If you prefer, you can add it to a small amount of juice.

How do I take Gavanci™? What is the recommended dosage?

Take 2 mL (poured into a spoon or mixed into ½ cup of water) twice daily — once in the morning on an empty stomach and once before bed. If taken with water, sip the mixture slowly over 1–2 minutes to allow the formula to coat your esophageal lining. Do not rush or gulp. The slow-sip method is key to how our product works.

Can I take Gavanci™ with my current medications or supplements?

Gavanci is designed with ingredients that complement most wellness routines. However, if you are taking prescription medications — especially PPIs, H2 blockers, blood thinners, or immunosuppressants — please consult your healthcare provider before starting Gavanci. This ensures there are no interactions specific to your situation.

How long does one bottle last?

Each bottle contains a 4-week supply when taken at the maintenance dose. For our recommended 90-Day Renewal Protocol — which uses a higher starting dose for the first phase — a 3-bottle bundle is the ideal starting point.

Is it safe for long-term use?

Yes. Our product is formulated with well-studied ingredients at safe, research-backed dosages. Unlike some acid-suppressing medications that may carry risks with extended use, our formula is designed to support your esophageal wellness as part of an ongoing daily routine. As always, consult your healthcare provider for personalized guidance.

How soon will I feel a difference?

Many customers report initial soothing comfort within minutes of their first dose, thanks to ingredients like marshmallow root and slippery elm that form a protective coating. For meaningful, lasting improvements in esophageal comfort, most people notice a difference within the first 2–4 weeks of consistent daily use. For the full benefit, we recommend completing our 90-Day Renewal Protocol.

What is the 90-Day Renewal Protocol?

The 90-Day Renewal Protocol is our recommended usage plan based on the biology of esophageal tissue turnover. It has four phases: Weeks 1–3 (Soothing Phase) where protective herbs begin calming tissue, Weeks 4–6 (Repair Phase) where barrier-supporting ingredients reinforce comfort, Weeks 7–9 (Strength Phase) where inflammation-calming compounds build resilience, and Weeks 10–12 (Renewal Phase) where your esophagus reaches a stronger, more comfortable baseline. Consistent daily use through all four phases delivers the best results.

What if I don't notice any improvement?

Individual results vary based on the nature and duration of your symptoms. If you have been using Gavanci consistently for 30+ days without noticeable improvement, please contact our support team at info@gavanci.com. We can discuss your experience and, if needed, process a full refund under our 90-Day Money-Back Guarantee. Your comfort is our priority.

I have Barrett's esophagus. Is Gavanci™ appropriate for me?

Barrett's esophagus is a serious medical condition that requires specialized care from a gastroenterologist. While Gavanci supports general esophageal health, it is not intended to diagnose, treat, or manage Barrett's or any other specific medical condition. We strongly recommend discussing any new supplement with your specialist, who can advise on what is appropriate for your individual care plan.

Will this help me get off my PPI or acid-blocking medication?

Gavanci is a dietary supplement designed to support esophageal comfort — it is not a replacement for prescribed medication. Never stop or change your medication without your doctor's guidance. Many customers use Gavanci alongside their existing care plan as complementary support. If your goal is to explore reducing medication, that conversation should happen with your prescribing physician.

Can it help with nighttime acid reflux or sleep disruption?

Many customers report that taking their evening dose of Gavanci about 30 minutes before bed helps support nighttime comfort. The formula's coating and soothing ingredients are designed to provide a protective layer. For best results, we also recommend elevating the head of your bed 6–8 inches and avoiding food 2–3 hours before sleep.

How do I cancel or modify my subscription?

You can cancel, pause, skip, or modify your subscription at any time on your own — either through the link in any of your order confirmation emails, or by logging into your account at gavanci.com. If you'd rather have us handle it for you, just email info@gavanci.com and we'll process your cancellation within 24 hours. No cancellation fees, no minimum commitment, no questions asked.